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## Overview
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deepTools is a comprehensive suite of Python command-line tools designed for processing and analyzing high-throughput sequencing data. This skill provides guidance for using deepTools to perform quality control, normalize data, compare samples, and generate publication-quality visualizations for ChIP-seq, RNA-seq, ATAC-seq, MNase-seq, and other NGS experiments.
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deepTools is a comprehensive suite of Python command-line tools designed for processing and analyzing high-throughput sequencing data. Use deepTools to perform quality control, normalize data, compare samples, and generate publication-quality visualizations for ChIP-seq, RNA-seq, ATAC-seq, MNase-seq, and other NGS experiments.
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**Core capabilities:**
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- Convert BAM alignments to normalized coverage tracks (bigWig/bedGraph)
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## When to Use This Skill
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This skill should be used when users request tasks involving:
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This skill should be used when:
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- **File conversion**: "Convert BAM to bigWig", "generate coverage tracks", "normalize ChIP-seq data"
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- **Quality control**: "check ChIP quality", "compare replicates", "assess sequencing depth", "QC analysis"
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