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Improve database description for more reliable skill calling

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Timothy Kassis
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scientific-databases/clinpgx-database/SKILL.md
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name: clinpgx-database
description: Toolkit for accessing ClinPGx, a clinical pharmacogenomics database providing information on how genetic variation affects drug response. Use this skill when working with pharmacogenomics data, querying gene-drug interactions, accessing CPIC clinical guidelines, retrieving allele function and frequency information, exploring PharmGKB annotations, or conducting research on personalized medicine and precision pharmacotherapy. ClinPGx consolidates PharmGKB, CPIC, and PharmCAT resources.
description: Comprehensive toolkit for accessing ClinPGx (Clinical Pharmacogenomics Database), the successor to PharmGKB providing clinical pharmacogenomics information on how genetic variation affects drug response, metabolism, efficacy, and toxicity. Use this skill for pharmacogenomics research, clinical decision support, gene-drug interaction queries, CPIC guideline access, allele function and frequency analysis, drug metabolism pathway exploration, personalized medicine implementation, precision pharmacotherapy, adverse drug reaction prediction, genotype-guided dosing, clinical annotation retrieval, drug label analysis, variant interpretation, phenotype prediction, population pharmacogenomics, medication therapy management, clinical trial screening, pharmacogene panel analysis, CYP450 enzyme interactions, transporter gene effects, HLA-associated drug reactions, immunosuppressant dosing, oncology drug toxicity, antidepressant response, anticoagulant therapy, pain medication metabolism, antiviral screening, cardiovascular drug interactions, and PharmDOG clinical decision support tool integration. ClinPGx consolidates PharmGKB, CPIC (Clinical Pharmacogenetics Implementation Consortium), PharmCAT, DPWG guidelines, FDA/EMA drug labels, and provides REST API access to curated pharmacogenomic knowledge for evidence-based clinical practice.
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# ClinPGx Database