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Better adherence to recommendations
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@@ -11,7 +11,7 @@ Facilitate access to and querying of the ChEMBL database, a manually curated rep
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## When to Use This Skill
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Use this skill when queries involve:
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This skill should be used when queries involve:
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- **Compound searches**: Finding molecules by name, structure, or properties
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- **Target information**: Retrieving data about proteins, enzymes, or biological targets
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@@ -13,7 +13,7 @@ The API is public (no authentication required) with a rate limit of approximatel
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## When to Use This Skill
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Use this skill when working with clinical trial data in scenarios such as:
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This skill should be used when working with clinical trial data in scenarios such as:
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- **Patient matching** - Finding recruiting trials for specific conditions or patient populations
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- **Research analysis** - Analyzing clinical trial trends, outcomes, or study designs
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@@ -11,7 +11,7 @@ Facilitate access to and querying of ClinPGx (Clinical Pharmacogenomics Database
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## When to Use This Skill
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Use this skill when queries involve:
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This skill should be used when queries involve:
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- **Gene-drug interactions**: Querying how genetic variants affect drug metabolism, efficacy, or toxicity
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- **CPIC guidelines**: Accessing evidence-based clinical practice guidelines for pharmacogenetics
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@@ -11,7 +11,7 @@ COSMIC (Catalogue of Somatic Mutations in Cancer) is the world's largest and mos
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## When to Use This Skill
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Use this skill when:
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This skill should be used when:
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- Downloading cancer mutation data from COSMIC
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- Accessing the Cancer Gene Census for curated cancer gene lists
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- Retrieving mutational signature profiles
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@@ -20,7 +20,7 @@ Access comprehensive FDA regulatory data through openFDA, the FDA's initiative t
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## When to Use This Skill
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Use this skill when working with:
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This skill should be used when working with:
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- **Drug research**: Safety profiles, adverse events, labeling, approvals, shortages
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- **Medical device surveillance**: Adverse events, recalls, 510(k) clearances, PMA approvals
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- **Food safety**: Recalls, allergen tracking, adverse events, dietary supplements
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@@ -11,7 +11,7 @@ Facilitate access to and querying of the GWAS Catalog, a comprehensive repositor
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## When to Use This Skill
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Use this skill when queries involve:
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This skill should be used when queries involve:
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- **Genetic variant associations**: Finding SNPs associated with diseases or traits
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- **SNP lookups**: Retrieving information about specific genetic variants (rs IDs)
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@@ -21,7 +21,7 @@ The Open Targets Platform is a comprehensive resource that supports systematic i
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## When to Use This Skill
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Use this skill when:
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This skill should be used when:
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- **Target discovery:** Finding potential therapeutic targets for a disease
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- **Target assessment:** Evaluating tractability, safety, and druggability of genes
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@@ -11,7 +11,7 @@ PubMed is the U.S. National Library of Medicine's comprehensive database providi
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## When to Use This Skill
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Use this skill when:
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This skill should be used when:
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- Searching for biomedical or life sciences research articles
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- Constructing complex search queries with Boolean operators, field tags, or MeSH terms
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- Conducting systematic literature reviews or meta-analyses
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@@ -11,7 +11,7 @@ Facilitate access to and querying of the ZINC database, a freely accessible repo
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## When to Use This Skill
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Use this skill when queries involve:
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This skill should be used when queries involve:
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- **Virtual screening**: Finding compounds for molecular docking studies
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- **Lead discovery**: Identifying commercially-available compounds for drug development
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