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Support for Ginkgo Cloud Lab
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scientific-skills/ginkgo-cloud-lab/SKILL.md
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name: ginkgo-cloud-lab
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description: Submit and manage protocols on Ginkgo Bioworks Cloud Lab (cloud.ginkgo.bio), a web-based interface for autonomous lab execution on Reconfigurable Automation Carts (RACs). Use when the user wants to run cell-free protein expression (validation or optimization), generate fluorescent pixel art, or interact with Ginkgo Cloud Lab services. Covers protocol selection, input preparation, pricing, and ordering workflows.
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# Ginkgo Cloud Lab
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## Overview
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Ginkgo Cloud Lab (https://cloud.ginkgo.bio) provides remote access to Ginkgo Bioworks' autonomous lab infrastructure. Protocols are executed on Reconfigurable Automation Carts (RACs) -- modular units with robotic arms, maglev sample transport, and industrial-grade software spanning 70+ instruments.
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The platform also includes **EstiMate**, an AI agent that accepts human-language protocol descriptions and returns feasibility assessments and pricing for custom workflows beyond the listed protocols.
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## Available Protocols
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### 1. Cell Free Protein Expression Validation
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Rapid go/no-go expression screening using reconstituted E. coli CFPS. Submit a FASTA sequence (up to 1800 bp) and receive expression confirmation, baseline titer (mg/L), and initial purity with virtual gel images.
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- **Price:** $39/sample | **Turnaround:** 5-10 days | **Status:** Certified
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- **Details:** See [references/cell-free-protein-expression-validation.md](references/cell-free-protein-expression-validation.md)
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### 2. Cell Free Protein Expression Optimization
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DoE-based optimization across up to 24 conditions per protein (lysates, temperatures, chaperones, disulfide enhancers, cofactors). Designed for difficult-to-express and membrane proteins.
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- **Price:** $199/sample | **Turnaround:** 6-11 days | **Status:** Certified
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- **Details:** See [references/cell-free-protein-expression-optimization.md](references/cell-free-protein-expression-optimization.md)
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### 3. Fluorescent Pixel Art Generation
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Transform a pixel art image (48x48 to 96x96 px, PNG/SVG) into fluorescent bacterial artwork using up to 11 E. coli strains via acoustic dispensing. Delivered as high-res UV photographs.
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- **Price:** $25/plate | **Turnaround:** 5-7 days | **Status:** Beta
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- **Details:** See [references/fluorescent-pixel-art-generation.md](references/fluorescent-pixel-art-generation.md)
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## General Ordering Workflow
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1. Select a protocol at https://cloud.ginkgo.bio/protocols
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2. Configure parameters (number of samples/proteins, replicates, plates)
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3. Upload input files (FASTA for protein protocols, PNG/SVG for pixel art)
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4. Add any special requirements in the Additional Details field
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5. Submit and receive a feasibility report and price quote
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For protocols not listed above, use the **EstiMate** chat to describe a custom protocol in plain language and receive compatibility assessment and pricing.
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## Authentication
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Access Ginkgo Cloud Lab at https://cloud.ginkgo.bio. Account creation or institutional access may be required. Contact Ginkgo at cloud@ginkgo.bio for access questions.
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## Key Infrastructure
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- **RACs (Reconfigurable Automation Carts):** Modular robotic units with high-precision arms and maglev transport
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- **Catalyst Software:** Protocol orchestration, scheduling, parameterization, and real-time monitoring
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- **70+ integrated instruments:** Sample prep, liquid handling, analytical readouts, storage, incubation
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- **Nebula:** Ginkgo's autonomous lab facility in Boston, MA
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