mirror of
https://github.com/K-Dense-AI/claude-scientific-skills.git
synced 2026-01-26 16:58:56 +08:00
Add DrugBank access
This commit is contained in:
@@ -6,6 +6,7 @@
|
||||
- **ClinVar** - NCBI's public archive of genomic variants and their clinical significance with standardized classifications (pathogenic, benign, VUS), E-utilities API access, and bulk FTP downloads for variant interpretation and precision medicine research
|
||||
- **ClinicalTrials.gov** - Comprehensive registry of clinical studies conducted worldwide (maintained by U.S. National Library of Medicine) with API v2 access for searching trials by condition, intervention, location, sponsor, study status, and phase; retrieve detailed trial information including eligibility criteria, outcomes, contacts, and locations; export to CSV/JSON formats for analysis (public API, no authentication required, ~50 req/min rate limit)
|
||||
- **COSMIC** - Catalogue of Somatic Mutations in Cancer, the world's largest database of somatic cancer mutations (millions of mutations across thousands of cancer types, Cancer Gene Census, mutational signatures, structural variants, and drug resistance data)
|
||||
- **DrugBank** - Comprehensive bioinformatics and cheminformatics database containing detailed drug and drug target information (9,591+ drug entries including 2,037 FDA-approved small molecules, 241 biotech drugs, 96 nutraceuticals, 6,000+ experimental compounds) with 200+ data fields per entry covering chemical structures (SMILES, InChI), pharmacology (mechanism of action, pharmacodynamics, ADME), drug-drug interactions, protein targets (enzymes, transporters, carriers), biological pathways, external identifiers (PubChem, ChEMBL, UniProt), and physicochemical properties for drug discovery, pharmacology research, interaction analysis, target identification, chemical similarity searches, and ADMET predictions
|
||||
- **ENA (European Nucleotide Archive)** - Comprehensive public repository for nucleotide sequence data and metadata with REST APIs for accessing sequences, assemblies, samples, studies, and reads; supports advanced search, taxonomy lookups, and bulk downloads via FTP/Aspera (rate limit: 50 req/sec)
|
||||
- **Ensembl** - Genome browser and bioinformatics database providing genomic annotations, sequences, variants, and comparative genomics data for 250+ vertebrate species (Release 115, 2025) with comprehensive REST API for gene lookups, sequence retrieval, variant effect prediction (VEP), ortholog finding, assembly mapping (GRCh37/GRCh38), and region analysis
|
||||
- **FDA Databases** - Comprehensive access to all FDA (Food and Drug Administration) regulatory databases through openFDA API covering drugs (adverse events, labeling, NDC, recalls, approvals, shortages), medical devices (adverse events, 510k clearances, PMA, UDI, classifications), foods (recalls, adverse events, allergen tracking), animal/veterinary medicines (species-specific adverse events), and substances (UNII/CAS lookup, chemical structures, molecular data) for drug safety research, pharmacovigilance, regulatory compliance, and scientific analysis
|
||||
|
||||
Reference in New Issue
Block a user