Add COSMIC database

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Timothy Kassis
2025-10-19 18:22:29 -07:00
parent 68468a42c9
commit e5afb5f4ba
5 changed files with 784 additions and 2 deletions

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@@ -8,6 +8,7 @@ A comprehensive collection of ready-to-use scientific skills for Claude, curated
- **AlphaFold DB** - AI-predicted protein structure database with 200M+ predictions, confidence metrics (pLDDT, PAE), and Google Cloud bulk access
- **ChEMBL** - Bioactive molecule database with drug-like properties (2M+ compounds, 19M+ activities, 13K+ targets)
- **COSMIC** - Catalogue of Somatic Mutations in Cancer, the world's largest database of somatic cancer mutations (millions of mutations across thousands of cancer types, Cancer Gene Census, mutational signatures, structural variants, and drug resistance data)
- **GEO (Gene Expression Omnibus)** - High-throughput gene expression and functional genomics data repository (264K+ studies, 8M+ samples) with microarray, RNA-seq, and expression profile access
- **KEGG** - Kyoto Encyclopedia of Genes and Genomes for biological pathway analysis, gene-to-pathway mapping, compound searches, and molecular interaction networks (pathway enrichment, metabolic pathways, gene annotations, drug-drug interactions, ID conversion)
- **NCBI Gene** - Work with NCBI Gene database to search, retrieve, and analyze gene information including nomenclature, sequences, variations, phenotypes, and pathways using E-utilities and Datasets API
@@ -115,7 +116,6 @@ You can use Anthropic's pre-built skills, and upload custom skills, via the Clau
### Scientific Databases
- **UniProt** - Protein sequence and functional information database
- **COSMIC** - Catalogue of Somatic Mutations in Cancer
- **ClinVar** - Clinical significance of genomic variants
- **STRING** - Protein-protein interaction networks
- **European Nucleotide Archive (ENA)** - Comprehensive nucleotide sequence database